Cyclolab

MTA Excellent Research Site qualification

News 23 May, 2024

We are honored to announce that CycloLab has been awarded the esteemed designation of 'Research Site Recognized as Excellent' by the Hungarian Academy of Sciences (MTA), following the recommendation of the Research Institute Evaluation Council.

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Over 15000 reads of a CycloLab review on sulfobutylether-cyclodextrins

News 6 May, 2024

This review entitled ’Sulfobutylether-cyclodextrins: Structure, degree of substitution and functional performance’ was published in: F.G. Ramirez (Ed.) Cyclodextrins. Synthesis, Chemical Applications and Role in Drug Delivery, Nova Scuience Publishers, New York, 2015.

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New email address for commercial operations

News 5 December, 2023

Please note that Cyclolab implemented a new email address for commercial operations: commerce@cyclolab.hu

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Year-End Appreciation and Important Dispatch Information

News 5 December, 2023

Please be advised that our last dispatch date for the current year is December 13. In order to facilitate a smooth administrative process, we kindly request that you place any remaining orders for the year by December 7.

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Inaugural lecture of Prof. Szente at the Hungarian Academy of Sciences

News 22 September, 2022

Lajos Szente, one of the founders of CycloLab, now advisor at the company and professor at the Debrecen University held his inaugural lecture on 13th September on the occasion that he was elected a corresponding member of the Hungarian Academy of Sciences.

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1000 posts on Cyclodextrin News blog

News 22 September, 2022

On 19 September the post No. 1000 was published.

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The Hungarian Academy of Sciences elected Dr. Lajos Szente, Ph.D., D.Sc

News 20 September, 2022

In 2022, the Hungarian Academy of Sciences elected Dr. Lajos Szente, Ph.D., D.Sc., an original co-founder and former CEO (now Scientific Advisor) of CycloLab Ltd., as a Corresponding Member of the Academy.

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CycloLab at ICS 2022

News 23 June, 2022

CycloLab participated at the 20th International Cyclodextrin Symposium with 6 researchers. The total number of the Hungarian participants from 4 universities and 2 companies was 17.

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XX. International Cyclodextin Conference

News 20 June, 2022

We are proud to be a sponsor of the 20th International Cyclodextrin Symposium in Sicily, Italy.

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ICS2020 in Sicily concluded

News 20 June, 2022

The ICS 2020 expected so long was concluded on 17 June, Friday. The about 160 participants (the detailed statistics come soon) agreed on the importance of the personal meetings and discussions. The symposium gave this opportunity.

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The book chapter of CycloLab reached 11000 reads on ResearchGate

News 20 April, 2022

This is the most read publication of CycloLab.

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CycloLab awarded by 2021 Innovation Grand Prize

News 30 March, 2022

Cyclolab Ltd. has received The Hungarian Innovation Grand Prix for 2021 for the excipient of the SARS-CoV-2 antiviral drug.

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CycloLab’s publication has reached 3000 reads on ResearchGate

News 15 December, 2021

This paper is a review on CD applications in food.

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WEBINAR: Non-pharma uses of cyclodextrins

News 30 November, 2021

The next episode of the "Meet the experts" series will be held from 3 PM (CET) on December 6., 2021.

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Team building at Cyclolab

News 9 November, 2021

A team building was held at Cyclolab on September 23rd. The best moments are summarized in pictures and videos.

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Major change: a decisive step-forward with the shelf-life of Dexolve (SBECD) by CycloLab

News 27 September, 2021

The expiration date for the Dexolve batches has been extended.

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Meet the Experts: Cyclodextrins as active ingredients in the 21st century – Webinar of CycloLab

News 24 September, 2021

After the great success of the webinar held in May, 2021 a next webinar organized by CycloLab will be held from 3 pm on October 11, 2021.

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CycloLab’s new organic synthesis laboratory

News 23 September, 2021

CycloLab’s new organic synthesis laboratory - equipped with brand new equipments and expanded to a much larger area - was inaugurated at the beginning of July, 2021.

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Lajos Szente on Recent Trends in Food Applications of Cyclodextrins

News 21 September, 2021

Lajos Szente, former CEO of CycloLab, gave a talk on the recent trends in food applications of cyclodextrins at the meeting of the Food Science and Safety Working Group of the Hungarian Academy of Sciences (Sep 17, 2021).

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Cyclodextrins still in the Focus of Pharmaceutical Research in Hungary

News 21 September, 2021

Cyclodextrin research was well represented at the Annual Symposium of Pharmaceutical Chemistry and Technology Working Group of the Hungarian Academy of Sciences (Sep 20-21, 2021). As much as 5 of the 32 presentations were related to cyclodextrins.

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3 years anniversary of Cyclodextrin News Blog

News 9 August, 2021

Cyclodextrin News a monthly periodical of CycloLab was changed to a blog in August 2018.

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CycloLab appoints new leaders in key positions

News 1 July, 2021

As CycloLab continues to expand its workforce both in the production and the R&D arms of the company, two new leaders were named in key positions as of July 1, 2021.

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CycloLab at BIO Digital 2021

News 15 June, 2021

The yearly exhibition, conference and partnering event of the Biotechnology Innovation Organization (BIO), will be held between June 10-11 and June 14-18 digitally, it is named BIO Digital as last year.

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CycloLab collaborates with Daicel Corporation

News 31 May, 2021

Daicel Corporation, Japan and CycloLab Cyclodextrin R&D Laboratory, Ltd, Hungary have jointly published a white paper on the bitterness masking effect of β-cyclodextrin in the formulation of orally disintegrating tablets (ODTs) using Daicel's propriatery excipient mixture called Granfiller D.

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CycloLab at the online abridged version of the ICS-2020

News 18 May, 2021

As the International Cyclodextrin Symposium, ICS-2020 (Giardini Naxos, Sicily) has been postponed to 2022 an abridged virtual meeting was organized by Antonino Mazzaglia (CNR-ISMN, Messina) to be held on line on June 7, 2021. The program of the on-line symposium is available on the website of the symposium.

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CycloLab participates for the 4th time at Biotechgate, that will be held in May 3-7, 2021

News 22 April, 2021

Biotechgate Digital Partnering is focusing on companies developing drugs, diagnostics and medical devices. The main objective of the event is to provide a platform for business development in the field of licensing and collaboration.

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Statistics of the webinar on pharmaceutical applications of cyclodextrins

News 21 April, 2021

The webinar of CycloLab “Getting the best out of cyclodextrins” was held on Apr.15-16, 2021. Out of >500 registrations over 360 participants have followed the presentations.

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CycloLab’s paper reached 2500 reads on ResearchGate

News 12 April, 2021

The paper published in Critical Reviews in Food Science and Nutrition on „Cyclodextrins in Food Technology and Human Nutrition: Benefits and Limitations in 2012” reached 2500 reads and 94 citations.

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New product catalogue for 2021

News 29 March, 2021

CycloLab has updated its product catalogue, now containing an even wider range of products and competititve pricing guaranteed for the high quality cyclodextrins.

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Webinar on Applications of Cyclodextrins in the Pharma Industries

News 24 March, 2021

A webinar with the title „Meet the experts: Applications of Cyclodextrins in the Pharma Industries” to be held on April 15-16, 2021 is being organized by CycloLab.

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Collaboration for the evaluation of the antiviral potential of CDs

News 17 March, 2021

In May, 2020, CycloLab announced a collaboration, where University of California, Berkeley, Excivion and CycloLab teamed-up to evaluate the antiviral potential of cyclodextrins against SARS-CoV-2 and other viral infections. While the Covid-19 related results of this work are non public yet, we are happy to present non-confidential data on an also very important viral threat: Dengue virus.

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The book chapter of CycloLab reached 7000 reads on ResearchGate

News 24 February, 2021

The book chapter of Puskás et al. on „Sulfobutylether-cyclodextrins: Structure, degree of substitution and functional performance” achieved 7000 reads on ResearchGate.

This is the most read publication of CycloLab. The last 1000 reads were achieved in about 4 months.

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RotaChrom Technologies Partners With Cyclolab to Increase Production of COVID-19 Treatment

News 11 February, 2021

RotaChrom Technologies, the developer of the world's first industrial-scale Centrifugal Partition Chromatography (CPC) technology platform, announced today the launch of a collaboration with Cyclolab Cyclodextrin Research and Development Laboratory Ltd. (“Cyclolab''), a cyclodextrin research, development and manufacturing company. This strategic partnership between Cyclolab and RotaChrom aims to develop a more efficient and cost-effective process to purify Remdesivir, which is a widely used treatment option for COVID-19.

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PRESS RELEASE

News 1 February, 2021

Development of Autophagy Inducing Cyclodextrin Derivatives for Aging-associated Diseases

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Tamas Sohajda appointed as CEO of CycloLab

News 7 January, 2021

CycloLab, a company with unparalleled expertise in the manufacturing, design and formulation of cyclodextrins, announces the appointment of Tamas Sohajda as the Company’s Chief Executive Officer (CEO), succeeding the current CEO Gabriella Szejtli, who will remain the company’s Head of Production. In the last 4 years Tamas has served as the company's R&D Director and executive manager.

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Former CEO of Cyclolab at the Workshop of Cyclodextrin Society, Japan

News 9 December, 2020

Dr. Lajos Szente was invited to give a lecture on “History of Hungarian Cyclodextrin Research” on the virtual workshop of Cyclodextrin Society, Japan.

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First experiments in space for Covid-19 drug research

News 25 November, 2020

Hungarian companies InnoStudio Inc. and CycloLab Ltd. are going to investigate the potential effect of microgravity on the complex formation properties of remdesivir and SBECD.

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First experiment in space for COVID-19 drug research

News 11 November, 2020

Veklury®, a remdesivir-based medicament (i.e., remdesivir-SBECD complex) invented by Gilead Sciences Inc., has already been approved or authorized for temporary use in approximately 50 countries worldwide. Hungarian companies InnoStudio Inc. and CycloLab Cyclodextrin R&D Laboratory Ltd. are going to investigate the potential effect of microgravity on the complex formation properties of remdesivir and SBECD.

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CycloLab at CPhI China 2020

News 11 November, 2020

CPhI China & P-MEC China 2020 Virtual Expo Connect show will take place in Shanghai from 16th – 18th December, and a digital extension of the event – known as “Virtual Expo Connect” – will take place online from November 18th - December 18th.

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Presentation of Lajos Szente, former CEO of Cyclolab at the Hungarian Academy of Sciences

News 5 November, 2020

It is a great honor to our company that Lajos Szente, former CEO of company was invited to the program „Celebration of Science” to talk about the research and development related to Covid-19 pandemic (Nov. 4, 2020).

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The book chapter of CycloLab reached 6000 reads on ResearchGate

News 19 October, 2020

The book chapter of Puskás et al. on „Sulfobutylether-cyclodextrins: Structure, degree of substitution and functional performance” achieved 6000 reads on ResearchGate.
This is the most read publication of CycloLab. The last 1000 reads were achieved in 4 months.

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New Book on the History of Cyclodextrins with participation of CycloLab’s researchers

News 12 October, 2020

The book edited by Crini, G., Fourmentin, S. and Lichtfouse, E. will be published on November 2 2020 by Springer but is available online already.

CycloLab’s researchers participated in the writing of the following chapters:
Morin-Crini, N. et al. History of Cyclodextrins
Crini, G. et al. Professor Szejtli: The Godfather of Cyclodextrins
Fenyvesi, É. et al. History of Cyclodextrin Production in Hungary

https://www.springer.com/gp/book/9783030493073

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New publications with the participation of CycloLab

News 28 September, 2020

The following papers have been recently published in cooperation with different research groups:

Extraction of mycotoxin alternariol from red wine and from tomato juice with beta-cyclodextrin bead polymer
E Fliszár-Nyúl, Á Szabó, L Szente, M Poór
Journal of Molecular Liquids, 114180. https://doi.org/10.1016/j.molliq.2020.114180
Highly enhanced curcumin delivery applying association type nanostructures of block copolymers, cyclodextrins, and polycyclodextrins
NZ Nagy, Z Varga, J Mihály, A Domján, É Fenyvesi and É Kiss
Polymers2020, 12(9), 2167; https://doi.org/10.3390/polym12092167
Investigation of cytotoxicity and cell uptake of cationic beta-cyclodextrins as valid tools in nasal delivery
G Rassu, S Fancello, M Roldo, M Malanga, L Szente, R Migheli, E Gavini, P Giunchedi
Pharmaceutics 12 (7), 658. https://doi.org/10.3390/pharmaceutics12070658
Adsorption of sulfamethazine drug onto the modified derivatives of carbon nanotubes at different pH.
S Kunsági-Máté, P Noveczky, L Szente, B Lemli
Molecules (Basel, Switzerland) 25 (11). https://doi.org/10.3390/molecules25112489
Modulation of plasma membrane composition and microdomain organization impairs heat shock protein expression in B16-F10 mouse melanoma cells
T Crul, B Csoboz, I Gombos, A Marton, M Peter, G Balogh, C Vizler, L Szente, L Vigh
Cells 9 (4), 951. https://doi.org/10.3390/cells9040951

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CycloLab’s submission to InnoCentive Challenge 9934291 - New Technologies to Prevent the Transmission of Coronavirus led to a favorable evaluation.

News 18 September, 2020

CycloLab’s proposal aimed at new technology to improve mask performance against novel viruses such as SARS, MERS, and COVID-19 by using cyclodextrin.

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Cyclodextrin on the website of European Commission

News 15 July, 2020

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE is searching for collaboration partners and investors for developing modified cyclodextrins which can irreversibly block and damage viruses.

https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/horizon-results-platform/23010;needList=7

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The book chapter of CycloLab reached 5000 reads on ResearchGate

News 19 June, 2020

The book chapter of Puskás et al. on „Sulfobutylether-cyclodextrins: Structure, degree of substitution and functional performance” achieved 5000 reads on ResearchGate.

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International Cyclodextrin Symposium – postponed to 2021

News 9 June, 2020

The International Cyclodextrin Symposium (ICS2020) organized by the National Council of Research (CNR) and the University of Messina, Italy to be held in Giardini Naxos (Messina, Sicily) was further postponed to 7/10 June 2021.

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Technology Presentation and Company Introduction for BIO 2020

News 27 May, 2020

CycloLab Ltd. prepared a presentation for BIO 2020 Digital to introduce our company and the various possible uses of cyclodextrins.

https://youtu.be/Qbs-VFGkeMI

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University of California, Berkeley, Excivion and CycloLab team-up to develop the antiviral potential of cyclodextrins against SARS-CoV-2

News 7 May, 2020

UC Berkeley, Excivion and CycloLab announce a supplemental grant awarded to UC Berkeley by the National Institutes of Health to evaluate a wide range of cyclodextrins as a potential treatment against SARS-CoV-2 (agent of COVID-19 disease).

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Ongoing clinical trials with SBECD formulated remdesivir

News 24 April, 2020

There are several pre-clinical and clinical studies going on using remdesivir formulated by SBECD.

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The book chapter of CycloLab reached 4500 reads on ResearchGate

News 16 April, 2020

The book chapter of Puskás et al. on „Sulfobutylether-cyclodextrins: Structure, degree of substitution and functional performance” achieved 4500 reads on ResearchGate.

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CycloLab picks up the gauntlet to fight coronavirus

News 9 April, 2020

The unexpected and sudden outbreak along with the quick spread of the coronavirus disease and rapid increase of the cases draw a sudden need for SBECD globally. CycloLab is now making extra efforts and has started manufacturing campaigns with extra shifts to do its best in these troubled times.

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New publications by participation of CycloLab

News 11 March, 2020

The following papers have been recently published in cooperation with various research groups:

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CycloLab picks up the gauntlet to fight coronavirus

News 6 March, 2020

The novel coronavirus SARS-CoV-2 is affecting 65 countries and territories around the world with almost 90,000 reported cases and almost 3,000 deaths. This week, the WHO declared that it was too early to call the outbreak a pandemic but countries should be “in a phase of preparedness”. While there’s no proven treatment yet for the virus and the pneumonia it causes, there are more than 70 drugs or drug combinations potentially worth trying, according to the World Health Organization.

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Prof. Kaneto Uekama awarded

News 25 February, 2020

Prof. Kaneto Uekama (Professor Emeritus of Kumamoto University, Advisor of the Society of Cyclodextrins, Japan) was awarded the Order of the Sacred Treasure, Gold Rays with Neck Ribbon.

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Genetics Prof. Vellai at CycloLab

News 17 February, 2020

Prof. Tibor Vellai, Department of Genetics, Faculty of Science, Eötvös Loránd University gave a lecture at CycloLab on the biochemical background of ageing.

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Lajos Szente awarded honorary professor at Debrecen University

News 10 February, 2020

Lajos Szente founder and former CEO of CycloLab was appointed to the title honorary professor on 31 January 2020 recognizing his lectures in the frame of industrial biochemistry to undergraduate students for 12 years.

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4000 Reads of book chapter on SBECD

News 3 February, 2020

The book chapter on ”Sulfobutylether-cyclodextrins: Structure, degree of substitution and functional performance” complied by CycloLab’s scientists in 2015 has reached a milestone of 4000 reads on ResearchGate.

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New publication by contribution of CycloLab

News 22 January, 2020

The following paper has been recently published in Int. J. Pharm:

György Trencsényi, Adrienn Kis, Judit P. Szabó, Ágnes Ráti, Katalin Csige, Éva Fenyvesi, Lajos Szente, Milo Malanga, Gábor Méhes, Miklós Emri, István Kertész, Miklós Vecsernyés, Ferenc Fenyvesi, István Hajdu:

IN VIVO PRECLINICAL EVALUATION OF THE NEW 68GA-LABELED BETA-CYCLODEXTRIN IN PROSTAGLANDIN E2 (PGE2) POSITIVE TUMOR MODEL USING POSITRON EMISSION TOMOGRAPHY

International Journal of Pharmaceutics 576 (2020) 118954 DOI:10.1016/j.ijpharm.2019.118954

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CycloLab’s polymer for atherosclerosis

News 15 January, 2020

Kim et al. reported in Journal of Controlled Release on recent results obtained by using beta-cyclodextrin polymer of CycloLab.

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CycloLab partner organization in BactiVax project

News 17 December, 2019

The kick-off meeting of Marie- Skłodowska-Curie Innovative Training Network “BactiVax” within the Horizon 2020 Programme of the European Commission was held in the last week.

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International Cyclodextrin Symposium 2020: Call for abstracts

News 9 December, 2019

The International Cyclodextrin Symposium (ICS2020) organized by the National Council of Research (CNR) and the University of Messina, Italy will be held on May 26-29, 2020 in Giardini Naxos (Messina, Sicily).

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New publications by contribution of CycloLab

News 4 December, 2019

The following papers have been recently published:

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Cyclolab’s survey on technical training

News 20 November, 2019

CycloLab started a survey to see if there is an interest in participating in technical training on cyclodextrin formulations.

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Enrollment in its Phase I Trial to Evaluate Trappsol® Cyclo™ for the Treatment of Niemann-Pick Disease Type C completed

News 31 October, 2019

Cyclo Therapeutics, Inc. announced that it has completed patient enrollment in its Phase I trial to evaluate the safety and tolerability of Trappsol^® Cyclo™ administered intravenously to Niemann-Pick Disease Type C (NPC) patients.

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CycloLab at EuroCD2019

News 9 October, 2019

EuroCD 2019 organized by the University of Santiago de Compostela was successfully held on October 2–4, 2019. It was an excellent conference of high scientific level which gave the opportunity also to students to introduce their works. CycloLab in collaboration with various research groups co-authored 9 posters and one oral presentation.

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Amgen's Kyprolis, J&J's Darzalex team up on myeloma survival win

News 1 October, 2019

Adding Johnson & Johnson’s Darzalex (daratumumab, a monoclonal antibody) to a combination of Amgen’s Kyprolis (carfilzomib formulated by SBE-BCD) and the steroid dexamethasone cut patients’ risk of disease progression or death by 37% compared with Kyprolis and dexamethasone alone.

Read more...

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New publications by contribution of CycloLab

News 25 September, 2019

The following papers have been recently published.

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New data on efficacy and stability of Mavenclad

News 17 September, 2019

Merck announced the presentation of new data proving the long-term efficacy and stability of Mavenclad (HPBCD formulated cladribine) against relapsing forms of multiple sclerosis.

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EuroCD 2019: The lists of speakers and poster presenters published

News 9 September, 2019

EuroCD organized by the University of Santiago de Compostela will be held on October 2–4, 2019.

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New publications by contribution of CycloLab

News 4 September, 2019

CycloLab continues publication activity. Four papers have been recently published.

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Prof. Jindrich Jindrich visited CycloLab

News 22 August, 2019

Prof. Jindrich Jindrich has visited CycloLab and gave a talk on stereospecific modification of cyclodextrins.

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New product catalogue

News 12 July, 2019

CycloLab has updated its product catalogue, now containing an even wider range of products and competititve pricing guaranteed for the high quality cyclodextrins.

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Smallest cyclodextrins synthesized

News 19 June, 2019

Hidetoshi Yamada and coworkers at Kwansei Gakuin University report that they have chemically synthesized the smallest possible cyclodextrins, CD3 and CD4 (Science 2019, DOI: 10.1126/science.aaw3053).

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CycloMolder software

News 16 April, 2019

A new software for modeling cyclodextrin derivatives and their complexes has been introduced.

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FDA approval of SBECD-enabled Brexanolone

News 27 March, 2019

Sage Therapeutics, a biopharmaceutical company announced that the U.S. Food and Drug Administration (FDA) has approved ZULRESSO^TM (brexanolone) injection for the treatment of postpartum depression (PPD).

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CycloLab at DUPHAT

News 5 March, 2019

Dubai International Pharmaceutical & Technology Conference & Exhibition (DUPHAT) held in Dubai on Feb. 26-28, 2019 is the premier pharmaceutical and technology event in the Middle East and North Africa. CycloLab's representatives could meet with local companies and understand how the pharmaceutical trade works in this region.

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Prof. Hidetoshi Arima visited CycloLab

News 6 December, 2018

Prof. Arima (Kumamoto University) has visited CycloLab and gave a talk on the research of his team.

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Prof. Loftsson (University of Iceland) visited CycloLab

News 27 November, 2018

Prof. Loftsson (University of Iceland) visited CycloLab and gave a talk on the development of eye drops using Oculis technology.

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New product catalogue

News 16 November, 2018

CycloLab has updated its product catalogue, now containing an even wider range of products and competititve pricing guaranteed for the high quality cyclodextrins.

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Large-ring cyclodextrins in the CycloLab's portfolio

News 1 October, 2018

Large-ring cyclodextrins (LR-CD) consisting of ten (CD10, cyclomaltodecaose, ε-CD) to twelve glycopyranose units (CD12, cyclomaltododecaose, η-CD) have not been available previously in any larger amounts, but now these novel carbohydrate molecules are available at CycloLab.

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6-monoguanidino-6-monodeoxy-βCD · HCl

News 1 October, 2018

Cyclolab introduced this unique and versatile compound to its product list, as we think this could be a really useful for a myriad of different purposes due to its characteristics.

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2-O-monopropargyl-βCD

News 5 September, 2018

Cyclolab introduced this compound to its product list, as we think this could be a really useful tool for those interested in further modification of CDs and creation of really unique compounds.

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A new forum started on cyclodextrins

News 3 September, 2018

A blog named Cyclodextrin News has been recently launched (https://cyclodextrinnews.com/) with the purpose of being an independent source of information for news in the field of cyclodextrins (publications, patents, business news, etc.) not only for experts in the field but also students or industrial groups familiarizing with the application of these compounds.

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Molecules, Special issue “Cyclodextrin Chemistry 2018”

News 31 July, 2018

With Bernard Martel as guest editor Molecules has started to publish the papers in the special issue of Molecules.

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New books on cyclodextrins

News 31 July, 2018

Three new books on various aspects of cyclodextrin research and applications have been recently published.

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July-August issue of Cyclodextrin News

News 31 July, 2018

July-August issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Hydroxypropyl (HP)-αCD is More Effective than HPβCD Against Breast Cancer".

Click here to read...

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Annual National Niemann Pick Disease Foundation Conference

News 6 July, 2018

The Foundation organizes the 26th Annual NNPDF Family Conference to be held in Louisville, Kentucky from August 2nd to August 5th.

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Nanoaggregation on command

News 5 July, 2018

ScienceDaily reported on the effect of cyclodextrins as parts of synthetic receptors on the aggregation of proteins, recently published by Yu Liu et al. (Nankai University) in Angewandte Chemie.

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June issue of Cyclodextrin News

News 4 July, 2018

June issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Cyclodextrin Phosphates"

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Check out our brand new catalogue

News 21 June, 2018

CycloLab has updated its product catalogue, now containing an even wider range of products and competititve pricing guaranteed for the high quality cyclodextrins. Please download the brochure in pdf form.

Product list

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May issue of Cyclodextrin News

News 5 June, 2018

May issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Self-assembled Supramolecular Systems and New Findings in the Treatment of Niemann Pick Disease type C as Shown on the 19th International Cyclodextrin Symposium (ICS19)"

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Website of EUROCD 2019 opened

News 4 June, 2018

The 6th European Cyclodextrin Conference will be held in Santiago de Compostella on October 2–4, 2019.

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IV. International Cyclodextrin Summer School

News 4 June, 2018

The successful series of international summer schools organized by the Italian Cyclodextrin Society is continuing.

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Jozsef Szejtli Award in 2018

News 16 May, 2018

Nicolas Blanchemain, assistant professor at the University of Lille, received the 2018. Jozsef Szejtli Award, which was handed over by Lajos Szente, CEO of CycloLab Ltd. at the 19th International Cyclodextrin Symposium on April 29, 2018 in Tokyo.

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April issue of Cyclodextrin News

News 26 April, 2018

April issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Shift of paradigm on HPBCD as
cholesterol sequestering agent in cells".

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HPBCD-formulated Cladribin – a new CD-enabled drug formulation on the market

News 25 April, 2018

HPBCD-enabled Cladribine formulation has been authorized in Europe on 22.08.2017 under the trade name Mavenclad against multiple sclerosis.

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Lajos Szente received Derek Horton Award

News 5 April, 2018

Congratulations to Lajos Szente for being awarded by the American Chemical Society’s CARB Division with 2017 Derek Horton Award in Industrial Carbohydrate Chemistry.

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March issue of Cyclodextrin News

News 5 April, 2018

March issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Cyclodextrin-enabled Insulin Delivery".

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February issue of Cyclodextrin News

News 6 March, 2018

February issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Cyclodextrin-enabled Cannabinoid Formulations"

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Cyclodextrin Therapy for Alzheimer’s Disease

News 1 March, 2018

CTD Holdings, Inc. has entered negotiations with Kerwin Research Center, LLC to explore the use of cyclodextrins (HPBCD) in the treatment of Alzheimer disease based on the success of HPBCD (it received orphan drug registration against Niemann Pick type C disease, called also childhood Alzheimer disease).

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International Cyclodextrin Symposium, 19th

News 6 February, 2018

The scientific program of the 19th ICS has already been published on the website of the conference.

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CyclonHit project concluded

News 6 February, 2018

The final board meeting of CyclonHit project aiming at developing CD-based nanocarrier systems to fight against bacterial resistance was held on 26 January 2018 in Paris at ISMO (Institut des Sciences Moléculaires d'Orsay).

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January issue of Cyclodextrin News

News 6 February, 2018

January issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Cyclodextrin microparticles for ocular drug delivery targeted to the posterior segment of the eye".

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New product catalogue

News 3 January, 2018

CycloLab has updated its product catalogue, now containing an even wider range of products and competititve pricing guaranteed for the high quality cyclodextrins. Please download the brochure in pdf form.

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Nominate a colleague for the 2018 József Szejtli Award

News 20 December, 2017

CycloLab, founder of József Szejtli award is seeking nominations for the coming International Cyclodextrin Symposium (in Tokyo), where the Szejtli prize 2018 will be awarded.

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Szente, L., CEO of CycloLab received Gabor Denes award

News 19 December, 2017

Gabor Denes, a Hungarian-British electrical engineer, the inventor of holography was awarded for his invention with Nobel Prize of Physics in 1971. For his honor Gabor Denes award was founded by the Novofer Foundation to acknowledge creative researchers and engineers for outstanding technological innovations.

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Special offer for December

News 4 December, 2017

One time 25% discount on over 120 products if ordered in December.

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Cyclodextrin Database works again

News 30 November, 2017

Cyclodextrin KnowledgeBase developed by a team headed by CycloLab works again after a technical break.

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Ronald C.D. Breslow passed away

News 8 November, 2017

Ronald Breslow, professor at Columba University passed away on October 25. Among his various research in organic chemistry he made significant achievements in cyclodextrin chemistry, mainly on enzyme mimics, as well. He is considered one of the founders of biomimetic chemistry.

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Updated presentation on Sugammadex

News 7 November, 2017

We have updated our presentaion on Sugammadex, containing now a wider set of impurities, more data on Cyclolab's proprietary technology and analytical expertise. The presentation is available in the pipeline menu.

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October issue of Cyclodextrin News

News 7 November, 2017

October issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "ICD-based Drug and Gene Delivery Systems on the 5th European Cyclodextrin Conference".

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New Pipeline project at Cyclolab

News 3 November, 2017

Cyclolab has started manufacturing cyclodextrin derivatives to be used as non-viral RNA/DNA delivery systems.

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Cyclolab's Dexolve in Gilead's patent application

News 3 November, 2017

A patent application from Gilead Sciences Inc (CA, USA) on Intravenous Formulations of a late sodium current inhibitor has been publshed recently. The patent application specifically names Cyclolab's Dexolve under its claims as the main formulating excipient. The formulation is suitable for treat several cardiovascular diseases.

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Scientific collaboration with CycloLab

News 11 October, 2017

In the Chemical and Biochemical Engineering Quarterly has been published a new article with CycloLab's co-operation: "Gas Antisolvent Approach for the Precipitation of alfa-Methoxyphenylacetic Acid –(R)-1-Cyclohexylethylamine Diateromeric Salt"

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Hot sale in October!

News 4 October, 2017

In October, some of the products can be purchased at a discounted price (min. 15% ) while stocks last.

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August-September issue of Cyclodextrin News

News 2 October, 2017

August-September issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Itraconazole/HPBCD solution; 20 years on the market”.

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HPBCD slows the progression of NPC-1 Clinical trial results published in The Lancet

News 2 October, 2017

The result of a non-randomized, open-label, phase 1–2 trial was published in The Lancet in August. It was concluded that intrathecal HPBCD decreased the neurological disease progression in Niemann-Pick disease type C1.

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Per-6-alkylthio CDs as Precursors of RNA/DNA/gene delivery systems

News 2 October, 2017

These compounds are the ideal substrates for the preparation of amphiphilic cyclodextrins.

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Abstract submission to the 9th Asian Cyclodextrin Conference (9ACC)

News 29 August, 2017

9ACC will be held on 14–17 December 2017 in Singapore organized by Jun Li (National University of Singapore).

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July issue of Cyclodextrin News

News 1 August, 2017

July issue of Cyclodextrin News has been uploaded to our website. The editorial is now on "Cholesterol-binding Cyclodextins for the Treatment of Cystic Fibrosis and Other Diseases with Pulmonary Surfactant Dysfunction”. View the current issue here.

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3D printed nanomachines based on cyclodextrins

News 31 July, 2017

Science Daily and other scientific internet portals reported on novel nanomachines able to convert chemical energy into mechanical work (lifting a coin) through solvent exchange.

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Abstract submission to 19th ICS started

News 31 July, 2017

Abstracts can be uploaded to the website of the 19th International Cyclodextrin Symposium from August 1 to September 16 using the template provided by the organizers.

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New product lines at CycloLab

News 19 July, 2017

As part of our new approach to application of CDs, we would like to draw your attention to a few derivatives and groups of products that have never been promoted before.

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CycloLab pipeline project

News 19 July, 2017

In order to have a better understanding of investors and partners on the status and potential of the ongoing projects, we have prepared a few slides for the following:

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New national project

News 13 July, 2017

Cyclodextrin-based traps to control cooperative action of bacteria.

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CD-based Water Cleaning Technology in Nature

News 5 July, 2017

Recent Nature (546/7657, published on 8 June 2017) reported on the novel CD-based sorbents for the removal of perfluorooctanoic acid (PFOA) from water.

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Sucampo has aquired Vtesse

News 5 July, 2017

Sucampo Pharmaceuticals Inc., a global biopharmaceutical company has aquired Vtesse, rare disease company.

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The current issue of Cyclodextrin News is available.

News 14 June, 2017

Please observe that this issue has been compiled in a novel format.

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Golf ball with CD-based rotaxane

News 7 June, 2017

A recently published US patent discloses a strange application of CDs: coating of golf balls with a mixture of polyurethane and CD-based polyrotaxane to provide excellent spin performance under wet conditions.

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Global Sulfobutyl Ether Beta-Cyclodextrin Market Research Report 2017

News 7 June, 2017

The market report focusing on the North American, European and Asia-Pacific regions gives forecast to 2021 on the world’s major market conditions.

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New CycloLab product list

News 10 May, 2017

CycloLab is delighted to present the freshly established product list that contains an even wider range of products than presented on the website and some clarification on the nature and uses of members in each product category. The full list is available to download as a pdf here.

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April issue of Cyclodextrin News

News 8 May, 2017

April issue of Cyclodextrin News has been uploaded to our website. The editorial is now on " Cyclodextrin-assisted reconstitution of membrane proteins”.

View the current issue here.

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CycloLab in the top 12 Manufacturers of Cyclodextrins

News 31 January, 2017

Worldwide Cyclodextrin Market Analysis and Forecasts 2017 has been compiled and now available. This report studies Cyclodextrin in Global market, especially in North America, Europe, China, Japan, Southeast Asia and India, focuses on top manufacturers in global market, with capacity, production, price, revenue and market share for each manufacturer.

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Clinical Study of HPBCD in Patients with NPC Disease at Karolinska University Hospital

News 21 December, 2016

CTD Holdings, Inc. received the approval of Swedish Medical products Agency to conduct a Phase I/II clinical trial evaluating intravenous application of Trappsol® Cyclo™ in patients with Niemann Pick type C (NPC) disease, a rare and fatal illness manifested in neurodegenerative, genetic lisosomal lipid metabolism disorder [1]. In addition to this Phase I/II study is being conducted in Europe, a US Phase I study will be started soon. The first patients are expected to be enrolled in the first quarter of 2017.

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Re-evaluation of β-cyclodextrin (E 459) as a food additive

News 21 December, 2016

The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) re-evaluated β-cyclodextrin (E 459) as a food additive. The Panel concluded that, based on the available toxicological database, there is no reason to revise the current ADI of 5 mg/kg bw per day for β-cyclodextrin.

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4628/full

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Culture of Chemistry

News 30 November, 2016

The book includes specially selected articles that previously appeared in The Chemical Intelligencer magazine published in the period of 1995–2000 [1]. Excerpts of these Editor's choice chapters chronicle the culture and history of chemistry, featuring great chemists and discoverers.

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With the help of cyclodextrins NASA prepares for first-ever in-space DNA sequencing experiment

News 30 November, 2016

Minion developed by Oxford Nanopore arrived to the international orbiting lab to start with the first-ever in-space DNA sequencer experiment. The MinION is a handheld device that weighs 120 g.

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Special Issue on Cyclodextrins

News 4 November, 2016

International Journal of Pharmaceutics will publish a special issue on cyclodextrins and cyclodextrin derivatives in drug development. This issue will contain reviews and original scientific papers that are focused on Professor Duchêne’s

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Study on Captisol Enabled Melphalan

News 12 October, 2016

The purpose of this study is to determine if the investigators can achieve a certain level of Captisol Enabled Melphalan that would be best to use in treating Multiple Myeloma and AL Amyloidosis. It is in the recruiting phase.

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3rd CYCLON-HIT Summer School

News 12 October, 2016

The 3rd CYCLON-HIT Summer School dedicated to „Photoactivable antbacterials: from basic concept to practical approaches” has been recently held in Bologna (September 26–28, 2016). The school organiozed by Ilse Manet (ISOF-CNR) and Salvatore Sortino (University of Catania) teaches the photophysical and photochemical principles and gives several examples of cyclodextrin applications in photodynamic therapy. The final program can be seen here:

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ENCAPSULATONS - New book from Academic Press

News 1 August, 2016

Volume 2 in the series of "Nanotechnology in the Agri-food Industry” with the title "Encapsulations” (edited by A.M. Grumezescu) has been recently published. It contains several chapters on cyclodextrin complexation of flavors and aromas.

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Alpha-CD tablets for animals

News 1 August, 2016

The recently marketed veterinary formulation is useful for improving the digestion of cats and dogs.

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György Kéri passed away

News 26 July, 2016

The world-wide recognized biochemist, Professor of Semmelweis University, György Kéri (66) passed away on 20th July after a long fight against an incurable disease. His outstanding research in the field of cell signaling therapy and related pharmaceuticals made him famous among professionals

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Global and Chinese Cyclodextrin Industry – 2016

News 15 July, 2016

Several professional and in-depth studies on the current state of various cyclodextrin industries with a focus on the Chinese market can be purchased from Reports Express. The following market research reports are available:

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18ICS finished with success

News 15 June, 2016

With about 80 participants from 15 countries the 18th International Cyclodextrin Symposium held on 18-21 May in Gainesville, USA was concluded with success.

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Internet web site on cyclodextrins

News 2 May, 2016

Ars Technica, web site on technology news (founded in Cambridge, Massachussetts) has published a paper on the latest findings of cyclodextrins on atherosceloris with the title: “Sweet drug clears cholesterol, reverses heart disease—and was found by parents”.*

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SBEBCD for FDA-Approved Cannabinoid-based Medications

News 1 February, 2016

Virio Health, LLC announced that it has entered into exclusive license and supply agreement with Ligand Pharmaceuticals, Inc. for Captisol to be used for the development of cannabinoid-based medications.

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Meridian Lab Announced Positive Outcome from Pre-NDA Meeting with FDA

News 1 February, 2016

Meridian Labs is a specialty pharmaceutical company focusing on the development of cancer treatments through formulation improvements.

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Cyclodextrins on the Cover of Nature

News 1 February, 2016

Novel porous βCD polymer was prepared and used for rapid removal of organic micropollutants from water. The crosslinking agent, tetrafluoroterephthalonitrile ensures rigid structure and high porosity improving the availability of the CD rings within the structure.

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Breakthrough Therapy designation to HPBCD of Vtesse

News 1 February, 2016

Vtesse, Inc, a rare disease company, announced that FDA granted Breakthrough Therapy designation to VTS-270 (a proprietary form of HPBCD) for the treatment of children with Niemann-Pick Disease Type C (NPC).

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