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6-monoguanidino-6-monodeoxy-βCD · HCl

News 1 October, 2018
Cyclolab introduced this unique and versatile compound to its product list, as we think this could be a really useful for a myriad of different purposes due to its characteristics. 
This BCD derivative bears one single guanidino moiety on the primary side and it is an appealing highly water soluble alternative to the amino counterpart. The guanidine-modified cyclodextrins are highly biocompatible compounds and not toxic. These properties were exploited for constructing small molecules/vectors able to interact with DNA (https://pubs.rsc.org/en/content/articlehtml/2007/ob/b614899a) and for building-up targeting molecules able to cross multiples biological membranes (https://onlinelibrary.wiley.com/doi/full/10.1002/chem.200701650)

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