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The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) re-evaluated β-cyclodextrin (E 459) as a food additive. The Panel concluded that, based on the available toxicological database, there is no reason to revise the current ADI of 5 mg/kg bw per day for β-cyclodextrin.
 
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4628/full