Sulfobutylated beta-cyclodextrin sodium salt (DS~4)

(CODE: 50)


Abbreviation: SBECD4
CAS Number: 182410-00-0
Product Number: 50
Cyclodextrin type: Anionic cyclodextrins
Quality: standard grade
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Chemical and Physical Description
Average Molecular Formula C42H70-nO35 · (C4H8O3SNa)n
Average Formula Weight 1135.0 + n·(158.2)
Possible impurities 4-Hydroxybutane-1-sulfonic acid sodium salt, bis(4-sulfobutyl) ether disodium, residual BCD
Solubility
(in 100 cm3 solvent, at 25 °C)
Water: > 50 g
Methanol: < 0.5 g
Acetone: < 0.5 g
Specification
Test Method Range
Appearance Visual white or off-white powder
Identification CE (USP <1053>) meets the requirements of average degree of substitution
Purity Calculated
(on dry substance)
> 95%
Limit of BCD (Betadex) HPLC (USP <621>) NMT 1.5% on the anhydrous basis
Limit of 1,4-butane sultone GC (USP <621>) NMT 5 ppm
Limit of 4-hydroxybutane-1-sulfonic acid CE (USP <1053>) NMT 2.5%
Limit of bis(4-sulfobutyl) ether disodium CE (USP <1053>) NMT 0.05%
Clarity of solution (30%, w/v) Visual the solution is clear, and essentially free from particles of foreign matter
Average Degree of Substitution (n) CE (USP <1053>) 3.5 - 4.5
pH (30%, w/v ) USP <791> 4.0 - 6.8
Phosphate content USP <851> 125 - 300 μg/g
Water content USP <921> Method I NMT 10.0%
Comments: only for reagent and laboratory purposes, not for human use.

Storage: at room temperature, in tightly closed container.

MSDS Downloads

  • 47-SBECD

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