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Pharma grade cyclodextrins
Research grade cyclodextrins
Analytical standards
Sugammadex related impurities (analytical standards)
Anionic cyclodextrins
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HPLC columns
QD
(2-Hydroxypropyl)-beta-cyclodextrin (DS~6.0)
(CODE: 28)
Abbreviation:
HPBCD
CAS Number:
128446-35-5
Product Number:
28
Cyclodextrin type:
Randomly substituted, non-ionic
Quality:
Pharma grade
for
0.00
EUR
Get a quote
Chemical and Physical Description
Average Molecular Formula
C
42
H
70-n
O
35
· (C
3
H
7
O)
n
Average Formula Weight
1135.0 + n·(58.1)
Possible impurities
Propylene glycol, beta-cyclodextrin, hydroxypropylated linear dextrins
Solubility
(in 100 cm
3
solvent, at 25 °C)
Water: > 33 g
Methanol: > 33 g
DMF: > 33 g
Specification
Test
Method
Range
Appearance
Visual
white or almost white, amorphous or crystalline powder
Identification A
IR (EP 2.2.24)
complies with reference standard
Identification B (Appearance of solution)
EP 2.2.1, EP 2.2.2 Method II
1 g dissolved in 2 mL of water with heating is clear and colorless and remains so after cooling
Conductivity (25 °C, 1% solution in water)
EP 2.2.38
max. 200 µS/cm
Related substances
residual BCD
propylene glycol
total other impurities
HPLC (EP 2.2.29)
GC (EP 2.2.28)
HPLC (EP 2.2.29)
max. 1.5%
max. 2.5%
max. 1.0%
Heavy metals
EP 2.4.20
Cd max. 0.2 ppm
Pb max. 0.5 ppm
As max. 1.5 ppm
Hg max. 0.3 ppm
Co max. 0.5 ppm
V max. 1 ppm
Ni max. 2 ppm
Average Degree of Substitution (n)
NMR (EP 2.2.33)
2.8 - 10.5 (molar substitution: 0.4 - 1.5)
Microbial contamination
EP 2.6.12, EP 2.2.13
TAMC: max. 10
3
CFU/g
TYMC: max. 10
2
CFU/g
Salmonella: absent/10 g
E.Coli: absent/1 g
Bacterial endotoxin (if intended for parenteral use)
EP 2.6.14
<10 IU/g
Loss on drying
EP 2.2.32
max. 10.0%
Storage:
at room temperature, in tightly closed container.
MSDS Downloads
MSDS_CY_2005_HPBCDv2.4
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(2-Hydroxypropyl)-beta-cyclodextrin (DS~4.5)
(CODE: CY-2005.2)
Price:
€ 2.38 / g
Quality:
Fine chemical grade
for
2.38
EUR
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