Sulfobutylated beta-cyclodextrin sodium salt (DS~4)

(CODE: 50)

Abbreviation: SBECD4

CAS Number: 182410-00-0

Product Number: 50

Cyclodextrin type: Anionic cyclodextrins

Quality: Research grade

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Chemical and Physical Description

Average Molecular Formula	C₄₂H_70-nO₃₅ · (C₄H₈O₃SNa)_n
Average Formula Weight	1135.0 + n·(158.2)
Possible impurities	4-Hydroxybutane-1-sulfonic acid sodium salt, bis(4-sulfobutyl) ether disodium, residual BCD
Solubility (in 100 cm³ solvent, at 25 °C)	Water: > 50 g Methanol: < 0.5 g Acetone: < 0.5 g

Specification

Test	Method	Range
Appearance	Visual	white or off-white powder
Identification	CE (USP <1053>)	meets the requirements of average degree of substitution
Purity	Calculated (on dry substance)	> 95%
Limit of BCD (Betadex)	HPLC (USP <621>)	NMT 1.5% on the anhydrous basis
Limit of 1,4-butane sultone	GC (USP <621>)	NMT 5 ppm
Limit of 4-hydroxybutane-1-sulfonic acid	CE (USP <1053>)	NMT 2.5%
Limit of bis(4-sulfobutyl) ether disodium	CE (USP <1053>)	NMT 0.05%
Clarity of solution (30%, w/v)	Visual	the solution is clear, and essentially free from particles of foreign matter
Average Degree of Substitution (n)	CE (USP <1053>)	3.5 - 4.5
pH (30%, w/v )	USP <791>	4.0 - 6.8
Phosphate content	USP <851>	125 - 300 μg/g
Water content	USP <921> Method I	NMT 10.0%

Comments: only for reagent and laboratory purposes, not for human use.

Storage: at room temperature, in tightly closed container.

MSDS Downloads

47-SBECD