Alpha-cyclodextrin secondary standard

(CODE: -)

Price: € 115.75 / g

Abbreviation: ACD WS

CAS Number: 10016-20-3

Product Number: -

Cyclodextrin type: Native, non-ionic

Quality: Analytical standard grade

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Discount

Volume	Volume Discount	Price
from 1 g	0%	€ 115.75 / g

Complies with EP and USP Pharmacopoeia requirements.

Chemical and Physical Description

Molecular Formula	C₃₆H₆₀O₃₀
Formula Weight	972.9
Possible impurities	Other cyclodextrins, linear oligomers
Solubility (in 100 cm³ solvent, at 25 °C)	Water: > 10 g Methanol: < 1.0 g DMSO: > 10 g

Specification

Test	Method	Range
Appearance	FIZ-05/06	white of off-white powder
Identity	TLC-02/06	complies to EP reference
Identification A	Specific optical rotation, EP 2.2.7, USP <871S>	+147° to +152°
Identification B	HPLC, EP 2.2.29, USP<621>	complies to EP reference
Identification C	Iodine test based on the monographs	yellowish-brown precipitate is formed
Appearance of 1% aqueous solution	Visual (EP 2.2.1)	clear solution
pH of 1% aqueous solution	EP 2.2.3, USP<791>	5.0 - 8.0
Related substances residual BCD residual GCD sum of other impurities	HPLC, EP 2.2.29, USP<621>	max. 0.25% max. 0.25% max. 0.50%
Reducing sugars	as in EP and USP monographs	max 0.2%
Elemental impurities	USP<231>	Cadmium NMT 0.2 µg/g Lead NMT 0.5 µg/g Arsenic NMT 1.5 µg/g Mercury NMT 0.3 µg/g
Heavy metals	EP 2.4.8	max. 10 ppm
Light absorbing impurities (1%)	EP 2.2.25, USP<857>	A₂₃₀-A₃₅₀: max 0.10 A₃₅₀-A₇₂₀: max 0.05
Sulphated ash	EP 2.4.14, USP<281>	max. 0.1%
ACD content	HPLC (EP 2.2.29)	97.0 - 102.0%
ACD content	HPLC USP<621>	98.0-101.0%
Water content	USP<921>	max. 11.0%
Loss on drying	EP 2.2.32	max. 11.0%