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Sugammadex related impurities (analytical standards)
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Bis(6-deoxy-6-chloro)-hexakis(6-deoxy-6-(2-carboxyethyl)thio)-gamma-cyclodextrin
(CODE: CY-3248)
Price:
€ 73.61 / mg
Abbreviation:
Di-Cl-SGM
CAS Number:
-
Product Number:
CY-3248
Cyclodextrin type:
analytical standard
Quality:
Analytical standard grade
for
73.61
EUR
Add to basket
Discount
Volume
Volume Discount
Price
from 10 mg
0%
€ 73.61 / mg
from 25 mg
23%
€ 56.60 / mg
from 50 mg
48%
€ 37.70 / mg
from 100 mg
65%
€ 25.20 / mg
from 1 mg
0%
€ 73.61 / mg
Chemical and Physical Description
Molecular Formula
C
66
H
102-n
Cl
2
Na
n
O
44
S
6
Formula Weight
1863 + n
·
22
Solubility
(in 100 cm
3
solvent, at 25 °C)
Water: soluble
Specification
Tests and methods
Requirements
Identification 1
LC-MS
conforms to theoretical mass
Identification 2
NMR; EP 2.2.33
conforms to theoretical structure
Identification 3
IR; EP 2.2.24
conforms to theoretical structure
Purity as mixture of isomers
HPLC
1
; EP 2.2.29
>90%
Other cyclodextrin-related impurities
HPLC
1
; EP 2.2.29
<10%
Sodium formate content
CE; EP 2.2.47
<3%
Sodium content
CE; EP 2.2.47
<10%
Residual solvents
TGM-MS
<10%
Purity
calculated
2
to be reported
1
HPLC analysis is carried out on an Agilent Poroshell column, with H
3
PO
4
/ NH
3
buffer system at pH=2.6 and UV-Vis detection
2
Calculated purity = 100% - (Other cyclodextrin-related impurities + Sodium formate content + Residual solvents)
IMPORTANT:
the compound is supplied in slightly acidic form for stability reasons; the actual molar sodium content (n) is indicated on the Certificate of Analysis of each batch.
Notes:
the compound is a mixture of 4 isomers.
Comments:
only for reagent and laboratory purposes, not for human use.
Storage:
in deep freezer, under inert atmosphere, in tightly closed container.
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