6-deoxy-6-[(5/6)-fluoresceinylthioureido]-HPBCD

(CODE: CY-F-2005.1)

Price: € 83.48 / mg

Abbreviation: FITC-NH-HPBCD
CAS Number: -
Product Number: CY-F-2005.1
Cyclodextrin type: Fluorescent cyclodextrins
Quality: fine chemical grade
product_name
for 83.48  EUR
Discount
Volume Volume Discount Price
from 1 mg 0% € 83.48 / mg
from 11 mg 9% € 75.81 / mg
from 26 mg 17% € 68.99 / mg
Chemical and Physical Description
Average Molecular Formula C42H71-n-mNO34 ∙ (C21H12NO5S)n ∙ (C3H7O)m
Average Formula Weight 1134.0 + n∙(389.4) + m∙(58.1)
Possible impurities 6-deoxy-6-monoamino-HPBCD, free dye
Solubility
(in 100 cm3 solvent, at 25 °C)
Water: soluble
Absorbance λmax: 484 nm
λex: 458 nm
λem: 460 - 650 nm
Specification
Test Method Range
Appearance Visual slight yellow to orange powder
Average Degree of Substitution for FITC (n) NMR (EP 2.2.33) 0.5 - 1.0
Average Degree of Substitution for (2-hydroxy)propyl groups (m) NMR (EP 2.2.33) 2.0 - 5.0
Impurities:
free dye content
6-deoxy-6-monoamino-HPBCD

CE (EP 2.2.47)
CE (EP 2.2.47)

< 0.3%
< 20%
Comments: only for reagent and laboratory purposes, not for human use.
The fluoresceinyl moiety is located at C(6). The product is highly hygroscopic and dried to constant weight under 100 mbar vacuum at 50 ˚C.

Description: The fluorophore (5/6 isomeric mixture) is attached on the primary hydroxyl rim of the cyclodextrin, via a chemically stable thioureido group. Each cyclodextrin ring contains a fluorescent unit. (2-Hydroxy)propylation is random, but almost exclusively on the secondary hydroxyl rim. The material is water soluble, it dissolves in DMF and DMSO, but it precipitates in acetone.

Applications: Chemosensor, fluorescent microscopy, transport processes, host-guest complexation, femtosecond processes.

Storage: at 2-8 ˚C temperature, protected from direct light and heat in a tightly closed dark glass container.




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