Succinyl-(2-hydroxypropyl)-beta-cyclodextrin

(CODE: CY-2033)


Abbreviation: SuHPBCD
CAS Number: -
Product Number: CY-2033
Cyclodextrin type: Anionic cyclodextrins
Quality: fine chemical grade
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Chemical and Physical Description
Molecular Formula C42H70-n-mO35 · (C4H5O3)n · (C3H7O)m
Formula Weight 1135.0 + n (100.1) + m (58.1)
Possible impurities (2-Hydroxypropyl)-beta cyclodextrin; succinic acid
Solubility
(in 100 cm3 solvent, at 25 °C)
Water: > 10 g
Methanol: > 50 g
Chloroform: < 1 g
Acetone: < 1 g
Specification
Test Method Range
Appearance Visual white to slight yellow powder
Average Degree of Substitution (hydroxypropyl groups/CD ring) NMR (EP 2.2.33) 2.5-4.5
Average Degree of Substitution (succinyl  groups/CD ring) CE (EP 2.2.47) 3.0-5.0
Purity Calculated (on dry substance) > 95%
Succinid acid CE (EP 2.2.47) < 1.0%
Residual BCD content TLC (EP 2.2.27) < 5%
Light absorbing impurities (1%) UV-VIS (EP 2.2.25) A250-350nm: < 0.1 AU
A350-720nm: < 0.02 AU
Loss on drying 105°C, 4 h, in vac, P2O5 < 10.0%
Comments: only for reagent and laboratory purposes, not for human use.
Storage: at room temperature, in tightly closed container.




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