(2-Hydroxypropyl)-beta-cyclodextrin (DS~4.5)

(CODE: 27)

Abbreviation: HPBCD

CAS Number: 128446-35-5

Product Number: 27

Cyclodextrin type: Randomly substituted cyclodextrins, neutral

Quality: Research grade

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Chemical and Physical Description

Average Molecular Formula	C₄₂H_70-nO₃₅ · (C₃H₇O)_n
Average Formula Weight	1135 + n·(58.1)
Possible impurities	Propylene glycol, BCD, hydroxypropylated linear dextrins
Solubility (in 100 cm³solvent, at 25 °C)	Water: > 33 g Methanol: > 33 g DMF: > 33 g

Specification

Test	Method	Range
Appearance	Visual	white or almost white powder
Appearance of aqueous solution	Visual (EP 2.2.1, EP 2.2.2) Method II	1 g dissolved in 2 mL of water with heating is clear and colorless and remains so after cooling
Identification 1	IR (EP 2.2.24)	complies with reference
Purity	Calculated (on dry substance)	min. 90%
Molar substitution	NMR (EP 2.2.33)	0.6 - 0.9
Residual BCD	HPLC (EP 2.2.29)	max. 1.0%
Propylene glycol content	GC (EP 2.2.28)	max. 5.0%
Loss on drying	EP 2.2.32	max. 7.0%

Comments: only for reagent and laboratory purposes, not for human use.

Storage: at room temperature, in tightly closed container.

MSDS Downloads

HPBCD CY2005