Beta-cyclodextrin

(CODE: 33)


Abbreviation: BCD
CAS Number: 7585-39-9
Product Number: 33
Cyclodextrin type: Native, neutral
Quality: pharma grade
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Chemical and Physical Description
Molecular Formula C42H70O35
Formula Weight 1135.0
Possible impurities Other cyclodextrins, linear oligomers
Solubility
(in 100 cm3 solvent, at 25 °C)
Water: < 2.0 g
Methanol: < 1.0 g
DMSO: > 10 g
Specification
Test Method Range
Appearance Visual white or almost white powder
Identification A: Specific optical rotation EP 2.2.7 +160° to +164°
Identification B :  HPLC
EP 2.2.29  
conforms with reference
Identification C: Iodine test   yellow-brown precipitate
Appearance of 1% aqueous solution Visual (EP 2.2.1) clear and colorless solution
pH of 1% aqueous solution EP 2.2.3 5.0 - 8.0
Reducing sugars EP max. 0.2%
Light absorbing impurities (1%) UV-Vis (EP 2.2.25) A230 - A350: max. 0.10
A350 - A750: max. 0.05
Related substances
residual ACD
residual GCD
sum of other impurities
HPLC (EP 2.2.29)
max. 0.25%
max. 0.25%
max. 0.50%
Residual solvents GC (EP 2.2.28) max. 10 ppm trichloroethylene
max. 10 ppm toluene
Heavy metals EP 2.4.8 max. 10 ppm
Sulphated ash EP 2.4.14 max. 0.1%
BCD content HPLC (EP 2.2.29) 98.0 - 101.0%
Microbial contamination EP 2.6.12, EP 2.6.13 TAMC: <103 CFU/g
TYMC: <102 CFU/g
Salmonella: absent/10 g
E. Coli: absent/1 g
Loss on drying EP 2.2.32 max. 16.0%
Storage: at room temperature, in tightly closed container.

MSDS Downloads

  • CY2001-BCD

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